NEUROPATHY: Upper Extremity at Onset
Nerve Anatomy
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Overview
From WUSTL NeuromuscularMotor Neuron Disorders: Acquired ALS Distal Lower Motor Neuron Syndrome with anti-GM1 antibodies Multifocal Motor Neuropathy Pure motor syndromes of the hand Proximal lower motor neuron syndromes Monomelic amyotrophy (Hirayama syndrome) FOSMN Sensory neuronopathy Polyneuropathies Hereditary Glycyl tRNA Synthetase (GARS): HMN 5A; CMT 2D BSCL2: HMN 5B; SPG17 Amyloidosis (Carpal tunnel syndrome) Toxins Lead intoxication Dapsone Immune GBS CIDP: Upper extremity variant Mononeuritis multiplex Drugs: Vinca alkaloids Insulinoma + Neuropathy Local Nerve Lesions Cervical & Upper extremity Brachial Plex
Related Conditions
Shared genesAcute Motor (Axonal) Neuropathy (AMAN)
IIGQ1BGM1
Antibodies vs Glycolipids & Glycoproteins
GM1MAGGQ1B
C. Anti-GM1 Antibodies
GM1IGMGM1LMN
Chronic Immune Demyelinating Neuropathies: Variants
GD1AMOTORGM1
Features of motor syndromes: Likely response to therapy
GM1
Guillain-Barré-like syndrome with serum IgM binding to GalNAc-GD1a ganglioside
GD1AGM1PATHOLOGY
Lower Motor Neuron Syndrome: Proximal Arm Predominant 1,
GM1
Motor neuropathy-Motor neuron syndromes
GM1
External Resources
Data sourced from the Washington University Neuromuscular Disease Center. For clinical use, always refer to primary sources.