Acute Motor (Axonal) Neuropathy (AMAN)
Immune/AntibodyOMIM 191160
W
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Overview
From WUSTL NeuromuscularEpidemiology Geography More common: Japan, China, Mexico & 3rd world countries Rare: Most parts of United States Occasional: Europe Onset age: More common in children Male = Female Seasonal peaks Mexico & China: July to September (Rainy season) Japan: March for C jejuni + patients Prodrome Gastrointestinal: Diarrhea + Campylobacter jejuni titers in 67% Campylobacter jejuni in GBS Serotype associations O-19 (HS:19) type > 50% when Campylobacter culture positive Risk of acute neuropathy: 1 in 158 6x greater than after other Campylobacter infections Common in China & Japan Different isolates clon
OMIM Entries
Related Conditions
Shared genes"Classic" Guillain-Barré Syndrome
H131GD1A
Acute Immune Polyneuropathies
GD1APATHOLOGY
ACUTE NEUROPATHIES
GD1A
Antibodies vs Glycolipids & Glycoproteins
GM1MAGGQ1B
Bone Morphogenetic Proteins
II
C. Anti-GM1 Antibodies
GM1IGMGM1LMN
Cell Death/Damage: Mechanisms
MLKLMEMBRANEMLKLRIPK3II
Chronic Immune Demyelinating Neuropathies: Variants
GD1AMOTORGM1
External Resources
Data sourced from the Washington University Neuromuscular Disease Center. For clinical use, always refer to primary sources.