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"Classic" Guillain-Barré Syndrome

Immune/AntibodyOMIM 139393

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antibody/gbs.htm#"Classic" Guillain-Barré Syndrome

Overview

From WUSTL Neuromuscular

Autoantibodies Clinical features Electrodiagnostic Laboratory Morbidity Other features Pathology Prodrome Prognosis Therapy English translation: By Bassam Malo MD Epidemiology Incidence: 1 to 2/100,000/year Male: Female = 1.25: 1 Peak ages: Bimodal Children & Young adults > 55 years Zika infection: Colombia Winter month peak: United States, Australia & Asia Genetic risk factors 38 Familial cases Reported associations with occurrence, prognosis & severity of GBS Conflicting results FcγRIIa-H131 allele homozygosity (vs R131) 4 More common than in healthy controls Higher risk for severe disease t

OMIM Entries

OMIM #139393 OMIM #146790 OMIM #608603 OMIM #609145

Related Conditions

Shared genes

Acute Immune Polyneuropathies

Acute Motor (Axonal) Neuropathy (AMAN)

ACUTE NEUROPATHIES

Antibodies vs Glycolipids & Glycoproteins

Chronic Immune Demyelinating Neuropathies: Variants

Classification of Acute Immune Neuropathies

Demyelinating ataxic neuropathy with IgM binding to GalNAc-GD1a and GM2 gangliosides

GD1AACUTECHRONIC

Distal Motor Axonal Neuropathies: "Distal Lower Motor Neuron Syndromes"

External Resources

WUSTL Neuromuscular

Washington University Disease Center

Online Mendelian Inheritance in Man

Biomedical Literature

NCBI Expert-Authored Reviews

Portal for Rare Diseases

National Organization for Rare Disorders

Data sourced from the Washington University Neuromuscular Disease Center. For clinical use, always refer to primary sources.