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Bone Morphogenetic Proteins

Laboratory / DiagnosticsOMIM 600725
W
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lab/trophic.htm#Bone Morphogenetic Proteins 2

Overview

From WUSTL Neuromuscular

Transforming growth factor-β family Classes Decapentaplegic protein (Dpp) ; BMP2 ; BMP4 60A ; BMP5 ; BMP6 ; BMP7/OP1 ; BMP8a/OP2 ; BMP8b/OP3 BMP3 (Osteogenin) ; GDF10 BMP9; BMP10; Dorsalin-1 BMP12/GDF7 ; BMP13/GDF6 ; GDF5 GDF3/Vgr2 Vg1 ; Univin BMP14; BMP15; GDF1 ; Screw ; Nodal ; XNrI-3; Radar; Admp Mediate developmental processes: Stage-specific effects Cell survival Death (Apoptosis): Rhombencephalic neural crest cells by BMP4 Muscle BMP2: Stimulates conversion to bone pathway BMP7: Induces muscle cell proliferation Morphogenesis Act as gradients: Dpp, BMP2, BMP4 Promote differentiation of

OMIM Entries

OMIM #600725OMIM #601265OMIM #600799

Related Conditions

Shared genes
Acute Motor (Axonal) Neuropathy (AMAN)
IIGQ1BGM1
Cell Death/Damage: Mechanisms
MLKLMEMBRANEMLKLRIPK3II
Vici syndrome
IICLINICAL

External Resources

WUSTL Neuromuscular
Washington University Disease Center
OMIM
Online Mendelian Inheritance in Man
PubMed
Biomedical Literature
GeneReviews
NCBI Expert-Authored Reviews
Orphanet
Portal for Rare Diseases
NORD
National Organization for Rare Disorders

Data sourced from the Washington University Neuromuscular Disease Center. For clinical use, always refer to primary sources.