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POLYMYALGIA RHEUMATICA

Ion Channels / Membrane
W
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Overview

From WUSTL Neuromuscular

Diagnostic Criteria (Healy) Persistent pain (> 1 month) involving two of : neck, shoulders, pelvic girdle Morning stiffness (> 1 hour in duration) Abrupt onset of illness (< 2 weeks) Age: ≥ 50 years Erythrocyte sedimentation rate > 40 mm/hr Rapid response to prednisone (≤ 20 mg/day) Absensce of other disorders General features Epidemiology Female > Male: 2:1 White > African-American Northern hemisphere: Higher latitudes; Scan Frequency 12 to 65 per 100,000 in patients > 50 years England: Up to 400 per 100,000 in patients > 65 years Correlates with frequency of giant cell arteritis Genetic asso

Related Conditions

Shared genes
Inclusion Body Myositis (IBM)
VAMPIADRB1
Isaac's Syndrome
ACHRRIADRB1
Macrophagic Myofasciitis
DRB1
Sarcoidosis
TNFTNF-
Systemic connective tissue disorders & Vasculitis: Specific syndromes
TNF

External Resources

WUSTL Neuromuscular
Washington University Disease Center
PubMed
Biomedical Literature
GeneReviews
NCBI Expert-Authored Reviews
Orphanet
Portal for Rare Diseases
NORD
National Organization for Rare Disorders

Data sourced from the Washington University Neuromuscular Disease Center. For clinical use, always refer to primary sources.