Systemic connective tissue disorders & Vasculitis: Specific syndromes

Overview

Rheumatoid Arthritis: Neuropathy syndromes Vasculitic Neuropathy 43 Epidemiology 10% of all RA 35% to 63% of RA with systemic vasculitis Longstanding disease: ~ 15 years after onset of RA Clinical Onset: Acute or Subacute Common pattern: Mononeuritis multiplex Modalities: Sensory-Motor or Sensory Multifocal or Asymmetric in 2/3 Nerves involved Peroneal (90%) Popliteal (50%) Ulnar (35%) Median (15%) Prognosis Worse with Cutaneous vasculitis Peripheral neuropathy Low serum CH50 & C4 complement RA + Vasculitis: Course No treatment: 5 yr survival 10% Immunosuppression: 5 yr survival 80% Systemic a

OMIM Entries

Related Conditions

External Resources