Granulomatous & Inflammatory Myopathies with Anti-mitochondrial antibodies

Overview

Epidemiology Geography Tokyo: 11% of inflammatory myopathies France: 8% of IIM Female:Male = 15:9 Clinical Onset age: 33 to 72 years; Mean 49 years Systemic Primary biliary cirrhosis: 30%; Often asymptomatic Cardiac: 33% to 71% Arrhythmias: Atrial tachycardia Cardiomyopathy: Reduced ejection fraction Myocarditis 20% Associated with Biliary cirrhosis Muscle Weakness Proximal > Distal Arms & Legs Moderate degree: 3/5 to 4/5 Scapular winging Paraspinal (11%) Atrophy: 55% Respiratory: Reduced vital capacity 33% Course: Chronic 55% Skin rash: Uncommon Associated disorders Malignancy: 13%; Colon Oth

OMIM Entries

Related Conditions

External Resources