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TACHYKININS: SUBSTANCE P & NEUROKININS A AND B

Laboratory / DiagnosticsOMIM 162321
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Overview

From WUSTL Neuromuscular

General The tachykinins (SeeSwissProt ) are a family of amidated neuropeptides that share a carboxyl terminal sequence Phe-X-Gly-Leu-Met-NH2. Transmitters Precursors: Preprotachykinins Synthesizing enzymes: Peptidases Metabolizing enzymes: Metabolite: Peptide fragments Receptors Receptor subtypes AgonistsAntagonistsSecond messenger NK(1) SPOMe, GR 73632,Sar9Met(O2)11SP; Substance P GR82334, RP67580, CP-99994 PI; G-protein NK(2) GR 64349; Neurokinin A L-659877, SR48968,MEN10207, GR94800GR100679 PI; G-protein NK(3) Senktide; Neurokinin B GR138676 PI

OMIM Entries

OMIM #162321

Related Conditions

Shared genes
Itch: Anatomy & Physiology
NH2

External Resources

WUSTL Neuromuscular
Washington University Disease Center
OMIM
Online Mendelian Inheritance in Man
PubMed
Biomedical Literature
GeneReviews
NCBI Expert-Authored Reviews
Orphanet
Portal for Rare Diseases
NORD
National Organization for Rare Disorders

Data sourced from the Washington University Neuromuscular Disease Center. For clinical use, always refer to primary sources.