Itch: Anatomy & Physiology
Other NeuromuscularOMIM 600933
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Overview
From WUSTL NeuromuscularDefinitions Itch: Sensation resulting in an urge to scratch Hyperknesis: Excessive itch induced by stimuli that normally cause mild itch or pain Punctate Hyperknesis: Touch evoked itch Alloknesis: Considerable itch evoked by light tactile stimuli Itch: Peripheral Stimuli General Itch axons may be mechanically insensitive or sensitive Mustard oil: Stimulates axons conveying dysesthesias associated with itch Histamine pathway: Acute itch Histamine Mostly released by: Mast cells Other: Basophils; Keratinocytes Course Onset: Delay of 30 to 60 seconds Maximum: 2 to 3 minutes Duration: 10 minutes Af
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Data sourced from the Washington University Neuromuscular Disease Center. For clinical use, always refer to primary sources.