Lipids: General
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Overview
From WUSTL NeuromuscularBasic molecules: Fatty acids Fatty acid definitions Short chain: 4 to 8 carbons (C4 - C8) Medium chain: C8 � C12 Long chain: C12/C14 - C20: Examples Palmitic: C16 Stearic: C18 Linoleic: C18 Oleic: C18; Abundant in PN myelin Very long chain (VLC): > C22 Lipid in muscle Abundance: 0.2% of muscle fiber Location: Type 1 > Type 2 muscle fibers Fatty acids: Metabolism Metabolic pathways Mitochondria β-oxidation Most ATP production FA type: < C20 Peroxisome β-oxidation FA type: > C20 Microsome: ω & ω-1 oxidation Muscle FA type: Saturated long-chain Steps Entrance into cell cytoplasm: Through sarcopla
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Data sourced from the Washington University Neuromuscular Disease Center. For clinical use, always refer to primary sources.