Coenzyme Q10 Deficiency
W
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msys/myoglob.html#Coenzyme Q10 Deficiency
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Overview
From WUSTL NeuromuscularCoenzyme Q10 13 General properties Forms: Reduced (Ubiquinol) & Oxidized (Ubiquinone) Locations All human tissues Highest levels: Heart, Kidney & Liver Cellular location: Mitochondria; Many other organelles Synthesis: ≥ 10 genes required Functions Distributes electrons between Dehydrogenases, and Cytochrome segments of respiratory chain Transports electrons From: Complexes I & II; Electron transfer flavoproteins (ETF) To: Complex III in respiratory chain Allows proton extruded from mitochondrial matrix to intermembrane space Can act as Pro-oxidant, or Anti-oxidant: Both lipoproteins & Cell
Associated Genes
OMIM Entries
External Resources
Data sourced from the Washington University Neuromuscular Disease Center. For clinical use, always refer to primary sources.