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Axon: Caliber

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Overview

From WUSTL Neuromuscular

Axon diameter: Related to Neurofilament content Amount: More neurofilaments in larger axons Degree of phosphorylation Decreased phosphorylation: Neurofilaments more densely packed Increased phosphorylation: Side arms spread; Neurofilaments more widely spaced Myelination: Effects on neurofilaments Axons narrower in regions without myelin: Initial segment; Node of Ranvier Unmyelinated axons have more densely packed neurofilaments Size principles Large motor neuron Large axon Myelin: Thick; Long internodes Fast conduction velocity High threshhold to depolarization Type II muscle fibers innervated

Related Conditions

Shared genes
Schwann Cell Development
IIIBBJUN

External Resources

WUSTL Neuromuscular
Washington University Disease Center
PubMed
Biomedical Literature
GeneReviews
NCBI Expert-Authored Reviews
Orphanet
Portal for Rare Diseases
NORD
National Organization for Rare Disorders

Data sourced from the Washington University Neuromuscular Disease Center. For clinical use, always refer to primary sources.