Neuromuscular HOMEepAGE

neuromuscular.wustl.edu

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Other Muscle Features

MitochondrialLaboratory / Diagnostics

View full entry on WUSTL Neuromuscular

lab/mbiopsy.htm#Other Muscle Features

Overview

From WUSTL Neuromuscular

Inflammation General stains H&E Congo red Acid phosphatase Esterase Immunocytochemistry Immune myopathies: Immune cell patterns Lymphocyte predominant: T-cells > Macrophages Stains: T-cells (CD4, CD8); B-cells (CD20) CD4 + CD8 cells: Often with focal invasion of muscle fibers Associated disorders IM-VAMP Inclusion body myositis (IM-VAMP): CD4 + CD8 cells Polymyositis with Mitochondrial Pathology (PM-Mito): CD4 + CD8 cells BCIM: B-cell foci; Ectopic lymphoid structures Vasculitis: Lymphocytes > Macrophages Lymphorrhages (Myasthenia gravis): T-cells ± B-cells Checkpoint inhibitors: B-cells & T-c

Related Conditions

Shared genes

ACUTE MYOPATHY & NMJ DISORDERS

Asymmetric Myopathic Weakness

Axonal Sensory Neuropathies with Serum IgM binding to Trisulfated Heparin Disaccharide (TS-HDS)

HDSDISACCHARIDEMAG

CHRONIC IMMUNE POLYNEUROPATHIES: AXONAL

DERMATOLOGIC DISORDERS & NEUROMUSCULAR DISEASE

DERMATOMYOPATHIES, IMMUNE

Finger Flexion Weakness

Granulomatous Myopathies

External Resources

WUSTL Neuromuscular

Washington University Disease Center

Biomedical Literature

NCBI Expert-Authored Reviews

Portal for Rare Diseases

National Organization for Rare Disorders

Data sourced from the Washington University Neuromuscular Disease Center. For clinical use, always refer to primary sources.