Noradrenaline (NA) & Adrenaline (A)

Laboratory / Diagnostics

lab/catechol.htm#Noradrenaline (NA) & Adrenaline (A)

Overview

From WUSTL Neuromuscular

Transmitter Metabolism Precursors: L-Tyrosine (a) → L-DOPA (b) → Dopamine (c) → Noradrenaline (d) → Adrenaline Synthesizing enzymes: (a) Tyrosine hydroxylase, (b) L-aromatic amino acid decarboxylase, (c) Dopamine �-hydroxylase, (d) Phenylethanolamine-N-methyl transferase Metabolizing enzymes:MAO and COMT Metabolites: Vanillylmandelic acid (VMA) and3-methoxy-4-hydroxyphenylglycol (MHPG) Adrenoceptors ReceptorsubtypesTransmitter AgonistsAntagonistsSecond messenger α(1A) α(1C) NA > A A61603 KMD3213(+)-niguldipine5-methyluradipil Ca++: Influx into cell α(1B) NA = A . SpiroperoneAH1111OAChloroethyl

Related Conditions

Shared genes

CATECHOLAMINE-RELATED MOLECULES & DISORDERS

DOPASEGAWAOH-BIOPTERIN

External Resources

WUSTL Neuromuscular

Washington University Disease Center

PubMed

Biomedical Literature

GeneReviews

NCBI Expert-Authored Reviews

Orphanet

Portal for Rare Diseases

NORD

National Organization for Rare Disorders

Data sourced from the Washington University Neuromuscular Disease Center. For clinical use, always refer to primary sources.