MUSCLE BIOPSY STAINS & PROCEDURES
MitochondrialLaboratory / Diagnostics
W
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Overview
From WUSTL NeuromuscularCategory Method Utility Perimysial Vessels: Normal VvG stain Morphology Hematoxylin & Eosin Muscle fiber pathology; Nuclei Verhoeff van Gieson (VvG) Connective tissue; Vessel structure; Intramuscular nerve (Myelinated axons) Gomori trichrome Connective tissue; Nemaline rods Cytoplasmic bodies Fiber Type Enzymes (See MYH) Myofibrillar ATPase Muscle fiber type grouping or Atrophy ATPase pH 9.4 Myosin loss; Type 1 or 2 fiber atrophy ATPase pH 4.6Type 2B muscle fibers ATPase pH 4.3Type 2C (Immature) muscle fibersBlood vessels Oxidative Enzymes NADH-TR Muscle fiber internal architecture; Tubular ag
External Resources
Data sourced from the Washington University Neuromuscular Disease Center. For clinical use, always refer to primary sources.