Neuromuscular HOMEepAGE
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MAGNESIUM

Autosomal RecessiveAutosomal DominantIon Channels / MembraneOMIM 248250
W
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Overview

From WUSTL Neuromuscular

Magnesium Renal associations Dialysis: Associated with high levels Magnesium toxicity: More common when magnesium parenterally administered in renal failure Vascular calcification: Correlates inversely with serum magnesium levels Tendon reflexes: Reduced by high magnesium levels Myasthenia gravis: May produce exacerbation Acute flaccid paralysis May occur with high magnesium levels May be assocaited with NMJ disorder Oxaliplatin neurotoxicity: Ca++ & Magnesium may reduce toxicity Hypomagnesemia Clinical Seizures Tetany Paresthesias Weakness Genetic syndromes Primary hypomagnesemia ● Claudin 18

OMIM Entries

OMIM #248250OMIM #602014OMIM #607009OMIM #263800OMIM #600968OMIM #154020OMIM #601814

External Resources

WUSTL Neuromuscular
Washington University Disease Center
OMIM
Online Mendelian Inheritance in Man
PubMed
Biomedical Literature
GeneReviews
NCBI Expert-Authored Reviews
Orphanet
Portal for Rare Diseases
NORD
National Organization for Rare Disorders

Data sourced from the Washington University Neuromuscular Disease Center. For clinical use, always refer to primary sources.