Acute Immune Neuropathies: Facial Diplegia Variant (BFP)

Overview

Epidemiology Japanese & North American patients Prodrome Infectious symptoms in previous 4 weeks Frequency: 86% URI or Fever most common Clinical Onset Age: 18 to 65 years Limb numbness Bifacial weakness Progressive: Over weeks Asymmetric: Often Paresthesias Most patients Distal limbs May persist for months Strength: Normal or Mildly reduced Tendon reflexes: Reduced or Absent Other cranial nerves: Often normal Course Monophasic Nadir at 4 weeks Improvement over months Differential diagnosis Laboratory CSF: Albumino-cytologic dissociation Protein: 51 to 256 Cells: 1 to 8 Nerve conduction studie

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